We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission Here’s our process.
Medical News Today only shows you brands and products that we stand behind.
Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:- Evaluate ingredients and composition: Do they have the potential to cause harm?
- Fact-check all health claims: Do they align with the current body of scientific evidence?
- Assess the brand: Does it operate with integrity and adhere to industry best practices?
CBD cream for pain may help relieve aches and tension. Various companies now include CBD as an ingredient in a range of topical products. Some studies suggest CBD can treat physical pain and inflammation, though research is ongoing.
- Best overall CBDfx Muscle and Joint Cream | Skip to Review
- For athletes: Level Select CBD Sports Cream | Skip to Review
- Best gel: Lazarus Naturals CBD Muscle Gel | Skip to Review
- Most moisturizing: R&R Medicinals CBD Cream | Skip to Review
- For muscle pain: PlusCBD Pain Relief Muscle Cream | Skip to Review
- Best organic: Joy Organics Premium CBD Sports Cream | Skip to Review
- Best cooling: Aspen Green Muscle Relief Cooling Cream | Skip to Review
- Best warming: CBDistillery CBD Warming Cream | Skip to Review
- For a cream with menthol: Cornbread Hemp CBD Lotion + Menthol | Skip to review
- Best lightweight formula: FAB CBD CBD Cream | Skip to review
Is CBD legal?The 2018 Farm Bill removed hemp from the legal definition of marijuana in the Controlled Substances Act. This made some hemp-derived CBD products with less than 0.3% THC federally legal. However, CBD products containing more than 0.3% THC still fall under the legal definition of marijuana, making them federally illegal but legal under some state laws. Be sure to check state laws, especially when traveling. Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled.
CBD cream is a topical product that contains CBD oil alongside other ingredients.
CBD comes from the Cannabis sativa (C. sativa) plant. Companies may infuse CBD into a range of products, including:
THC is the compound, or cannabinoid, responsible for the “high” that people associate with cannabis. Some CBD products may contain up to 0.3% of THC in dry weight. Producers can isolate CBD from the THC compound so that CBD cream will not cause a person to feel high.
Medical News Today chooses products that meet the following criteria:
- Ingredients: MNT chooses products containing safe and high quality, clearly labeled ingredients. They should also confirm they are free from pesticides, heavy metals, and mold.
- Dosage: MNT chooses products that clearly state the CBD dosage and THC content.
- Serving size: MNT selects products in which manufacturers recommend a dosage and how to take it.
- Third-party labs: MNT chooses products that must undergo third-party testing for contaminants by an ISO 17025-compliant laboratory.
- Available certificate of analysis: MNT chooses companies that demonstrate transparency and share a product’s certificate of analysis (COA) after receiving its third-party lab results.
Please note that the writer of this article has not tried these products. All information presented is purely research-based and correct at the time of publication.
Medical News Today follows a strict product selection and vetting process. Learn more here.
The following table compares the CBD creams in this article on key features:
| Product | CBD type | Key ingredients | CBD strength | Size | Return/ refund | Price |
|---|---|---|---|---|---|---|
| CBDfx | broad-spectrum | white willow bark, caffeine, menthol | 1,000-3,000 mg | 50 ml | 60 days | $79.99-$129.99 |
| Level Select CBD | broad-spectrum | menthol | 900-1,800 mg | 85 g | 30 days | $29.99-$49.99 |
| Lazarus Naturals | full-spectrum | menthol, camphor, capsaicin | 600-2,000 mg | 30-100 ml | 90 days | $12-$32 |
| R&R Medicinals | full-spectrum | calendula flower, jojoba, arnica montana | 1,000 mg-2,000 mg | 2.5 fl oz | 60 days | $50-$70 |
| PlusCBD | full-spectrum | camphor, menthol | 500 mg | 4 oz | 90 days | $34.99 |
| Joy Organics | broad-spectrum | camphor, menthol | 1,000 mg | 118 ml | 90 days | $49.95 |
| Aspen Green | full-spectrum | organic jojoba seed oil, arnica extract, tea tree oil | 1,000 mg | 60 ml | 60 days | $84.99 |
| CBDistillery | isolate | camphor, sunflower seed oil | 500 mg | 1.7 fl oz | 60 days | $35 |
| Cornbread Hemp | full-spectrum | menthol | 500 mg | 2 fl oz | 30 days | $49.99 |
| FAB CBD | full-spectrum | aloe vera leaf extract, blood orange oil | 600 mg | 2 oz | 30 days | $49 |
People may wish to consider several factors before purchasing CBD cream, such as:
- COA: A person should only purchase CBD products from companies with COAs available for their products. These certificates verify that the products’ ingredient lists are correct and that the ingredients are generally not harmful to individuals.
- Ingredients: CBD creams may have different ingredients, such as camphor for a warming feel or menthol for a cooling effect.
- Spectrum type: CBD products typically come in full-spectrum and broad-spectrum formulas. Both contain cannabis plant extracts. However, full-spectrum CBD contains up to 0.3% THC, while broad-spectrum products do not contain any THC. A third type, CBD isolate, is pure CBD and contains no other cannabis plant compounds.
People can apply CBD cream to their skin like any other lotion. However, it is important to follow the instructions on the product packaging.
A person should perform a patch test before using a new CBD cream on their skin. If they experience a reaction to the product, they should stop using it and contact a doctor.
If a person experiences any reactions, such as redness or inflammation, they should stop using the product immediately and contact a healthcare professional.
Visit our dedicated hub for more research-backed information and in-depth resources on CBD.
Researchers have found that certain compounds in the cannabis plant may have beneficial effects, including:
A 2020 review found that CBD helped provide significant pain reduction.
A
Another
These animal studies have shown that CBD may ease neuropathic, inflammatory, and arthritis-related pain. CBD in oral, injectable, or gel form helped reduce inflammation and had analgesic, or pain-relieving, effects.
How does CBD help with pain?
CBD
- G protein-coupled receptors: CBD blocks several g protein receptors in the brain, including GPR3, GPR6, and GPR12, which may play a role in neuropathic pain development.
- Transporters: CBD binds to transporters in the endocannabinoid system, such as fatty acid-binding proteins. It also inhibits other transporters, producing anti-inflammatory effects.
- Enzymes: CBD inhibits certain enzymes and acids that have a role in inflammation.
- Nuclear factors: CBD interacts with nuclear factors in the body to produce anti-inflammatory effects.
- Transient receptor potential vanilloids (TRPVs): TRPV receptors play an important role in pain signaling. CBD blocks these receptors, which can lead to pain-relieving effects.
As the inclusion of CBD into health products is a relatively recent development, there is a lack of scientific research examining its long-term risks.
Generally, people tolerate CBD well. However, the
- drowsiness
- diarrhea
- decrease in appetite
- irritability
- agitation
The FDA also states that CBD use may have negative effects that people cannot notice, including potential liver damage and harm to fetuses.
The Food and Drug Administration (FDA) has only approved one CBD product, Epidiolex, a prescription medication for certain types of seizures.
Anyone taking medicines and considering using a CBD cream should also consult a doctor or qualified CBD clinician. These professionals can advise whether CBD will interact with the medication.
If a person does not want to try a CBD cream for their pain or if they wish to use it alongside other treatments, they may consider the following:
- Acupuncture involves trained practitioners inserting needles into specific points on the body. A 2021 systematic review concludes that many studies show benefits of acupuncture on lower back pain.
- Massage: An old case study involving a man with chronic back pain suggests that four massages over 20 days improved chronic back pain. However, more research is necessary to explore the benefits of massage for treating chronic back pain. A 2019 study examining the effects of massage on individuals with lower back pain concludes that a person’s perception of pain reduced after a massage. Massage may be more suitable for individuals with exercise-related back muscle soreness.
- Spinal manipulation: The
National Center for Complementary and Integrative Health suggests spinal manipulation may help relieve sciatica, lower back pain, and neck pain. - Exercise: According to research, engaging in exercise may reduce risk of lower back pain and other disability. The researchers recommend a combination of strengthening exercises with aerobic or stretching exercises two or three times a week.
Below, we answer some frequently asked questions about using CBD cream for treating pain:
How long does it take for CBD to relieve pain?
The time it takes to feel CBD’s effects differs between products. For example, sublingual CBD, which people place under the tongue, takes from 15 to 45 minutes to take effect.
The time it takes for CBD cream to relieve pain may also vary between individuals. A person should follow all product instructions carefully when using the cream.
How strong should CBD be to relieve pain?
CBD is available in different strengths. Companies should state how strong the CBD is in the product description. The more CBD in a product — usually in mg measurements — the stronger it is.
However, people should start at a lower strength or use less CBD cream. If necessary, they can gradually increase the strength or amount of CBD over time.
Are CBD products legal?
Individuals should always check state laws where they are residing or traveling to before using CBD products, to ensure that they are not breaking any state laws.
Hemp-derived CBD is legal federally. However, some states may class hemp-derived CBD as an illegal substance.
Cannabis-derived CBD is illegal federally but may be legal under certain state laws.
Does CBD cream heal the pain?
Research suggests that the use of CBD may help to manage chronic pain symptoms in adults. However, CBD products may help to relieve pain rather than eliminate it altogether temporarily.
Does topical CBD reduce inflammation?
Research from 2022 states that topical CBD may help to reduce inflammatory conditions, such as eczema. Further
CBD creams are products that a person applies to their skin. They may reduce pain and inflammation in individuals with pain.
Although CBD creams may provide some pain relief, people should seek guidance from a healthcare professional first to assess the underlying cause of their pain and receive medical treatment, if necessary.
People should also consult a doctor or pharmacist if they intend to use CBD products alongside prescription or nonprescription medications to reduce the risk of drug interactions and side effects.